MUTAGENS
Agent that include mutation are known as MUTAGENS. Mutagen may be different kind of radiation certain chemical . the different mutagen maybe group as follow
1. Physical mutagen
A. Ionizing radiation
i) particulate radiation that include x-ray, gamma ray,beta Ray etc
ii) non particulate radiation
B. Nonionizing radiation i.e ultraviolet radiation
2. Chemical mutagens
A. Alkylating agent- i.e sulphur mustards, nitrogen mustards, epoxides, imines(ethylene imine or EI), sulphates and sulphonate (ethylmethane sulphonate or EMS,methylmethane sulphonate or MMS),diazoalkanes,nitroso compounds, N-methyl-N-nitro-N-nitroso-guanidine or MNNG)
B. Acridine dyes- i.e acriflavine,proflavine,acridine orange,acridine yellow,ethidium bromide.
C. Base analogues i.e 5-bromouracil,5-chlorouracil.
D. other - nitrous acid, hydroxyl amine, sodium aside
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